FORMULATION AND EVALUATION OF SOLID DISPERSION OF TADALAFIL

Formulation and Evaluation of Solid Dispersion of Atorvastatin Calcium

The present study was designed to improve the solubility and hence enhance the dissolution of hydrophobic drug Atorvastatin calcium (ATC) in order to increase its bioavailability. Solid dispersion of atorvastatin calcium using carrier PEG 4000 was formulated in different ratios by conventional fusion and microwave induced fusion method. In particular, the Microwave technology has been considere...

Formulation and Evaluation of Solid Dispersion of Olanzepine

Formulation and Evaluation of Solid Dispersion of Olanzepine

The poor dissolution rate of water-insoluble drugs is still a major problem conforming the pharmaceutical industry. The most common method for improving the solubility is by increasing the surface area of the drug through micronization. But, in practice the effect of micronization is often disappointing, especially when the drugs are encapsulated or tablet. It is generally recognized that low s...

Formulation & Evaluation of Meloxicam Solid Dispersion Incorporated Topical Gels

Solid dispersion complexes of meloxicam were prepared by using cyclodextrins (BCD, HPBCD), PVP and urea by kneading method in different molar and weight ratios. The complexes were characterized by DSC and IR, suggested that no chemical interaction between drug and carrier. The solubility, dissolution and permeability was studied for prepared complexes. The solubility, dissolution and permeabili...

histological evaluation of the effect of three medicaments; trichloracetic acid, formocresol and mineral trioxide aggregate on pulpotomized teeth of dogs

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